How we rate.
Rating Methodology
Our evidence reviews are generated using a strict 5-part AI research workflow that extracts data directly from PubMed and clinical trial registries, followed by human verification.
Level 5: FDA Approved
Extensive phase 3 clinical trials, full regulatory approval, and massive human data pools.
Level 4: Strong Clinical Evidence
Approved in other countries, or robust off-label phase 2/3 trial data.
Level 3: Promising Clinical Data
Solid physiological research with some compelling human pilot studies.
Level 2: Meaningful Preclinical
Very strong animal and in-vitro data explaining mechanism, but lacking scaled human trials.
Level 1: Emerging Theoretical
Early stage animal or in-vitro models only. Extremely speculative.
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