INTRODUCTION

The active ingredient in Mounjaro and Zepbound. It mimics two natural hormones — GLP-1 and GIP — that control appetite, blood sugar, and metabolism. FDA-approved for Type 2 diabetes, with weight loss approval expanding.

What is this used for?

Weight Loss

Weight Loss

FDA-approved. Works through dual hormone pathways for potentially stronger appetite suppression than single-pathway medications.

Blood Sugar

Blood Sugar

FDA-approved for Type 2 diabetes. May offer stronger blood sugar control than single-pathway GLP-1 medications.

Metabolic Optimization

Metabolic Optimization

Clinical trials suggest the addition of the GIP hormone may result in fewer digestive side effects compared to older medications.

What dose is typical for your goal?

Weight Loss typical protocol
Typical dose
Starts at 2.5 mg, increases over months
How it's taken
Injection under the skin
How often
Once a week
Most common starting point
2.5 mg weekly for 4 weeks, then increases (5 mg → 7.5 mg → 10 mg → up to 15 mg)

Based on published studies and what providers typically prescribe.

Important safety info

  • Contraindicated if you or a family member has medullary thyroid carcinoma (MTC) or MEN 2 syndrome.
  • FDA-approved escalation: minimum 4-week intervals between increases of no more than 2.5 mg.
  • Maximum approved maintenance dose is 15 mg — provider-directed beyond 10 mg.

These are typical doses from research and real prescriptions — not a recommendation for you specifically. Your provider will adjust based on your body, your goals, and your health history.

Want your exact dose? A provider will personalize this for you.

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How do you take it?

RouteInjection under the skin
FrequencyOnce a week
Important Note

These are typical doses from research and real prescriptions — not a recommendation for you specifically. Your provider will adjust based on your body, your goals, and your health history.

What to expect

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Week 1-2

Strong early appetite suppression. Many people report this is stronger than other GLP-1 medications.

Week 3-6

Dose escalation phase. Your provider increases the dose gradually while you adjust.

Month 2-4

Primary weight loss phase. Average is 15-22% body weight loss over 12 months in clinical studies.

Month 4+

Long-term maintenance with provider guidance on when to taper.

Individual experiences vary. Results depend on your body, goals, and protocol adherence.

How well researched is this?

FDA Approved Medication

Approved for Type 2 diabetes (Mounjaro) and weight management (Zepbound). Thousands of participants across phase 3 trials.

Want the full breakdown? Read our comprehensive analysis.
Read Evidence Review →

Purity

Purity measures how clean and accurate the compound is. Higher purity means fewer contaminants and more reliable dosing.

>99.0%

HPLC Purity Tested

Always require a Certificate of Analysis (CoA) from a US-based compounding pharmacy.

Common questions

Ready to start?

Consult with a licensed provider to determine the right protocol for your goals.