TB-500 — What It's Used For, Typical Doses & Research | What The Pep

INTRODUCTION

A synthetic version of a protein your body makes naturally called Thymosin Beta-4. It plays a role in how your body heals wounds, builds new blood vessels, and reduces inflammation.

What is this used for?

Injury Recovery

Studied for healing tendons, ligaments, and muscles. Often combined with BPC-157 in what's called the Wolverine Stack.

Muscle Recovery

Studied for reducing soreness after intense workouts and speeding recovery between training sessions.

Flexibility & Mobility

Research suggests it may improve range of motion in stiff or previously injured joints.

What dose is typical for your goal?

Injury Recovery typical protocol

Typical dose: 2–2.5 mg
How it's taken: Injection under the skin
How often: Twice a week (loading), then once a week
Most common starting point: 2 mg twice a week for 4–6 weeks (loading phase), then 2 mg once a week

Based on published studies and what providers typically prescribe.

These are typical doses from research and real prescriptions — not a recommendation for you specifically. Your provider will adjust based on your body, your goals, and your health history.

Want your exact dose? A provider will personalize this for you.

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How do you take it?

RouteInjection under the skin

FrequencyTwice a week

Important Note

These are typical doses from research and real prescriptions — not a recommendation for you specifically. Your provider will adjust based on your body, your goals, and your health history.

What to expect

1 / 4

Days 1-14

Loading phase. Most people don't feel dramatic changes yet, but tissue repair is happening beneath the surface.

Week 3-4

Improved range of motion and reduced stiffness commonly reported. Recovery between workouts feels faster.

Week 5-6

Full systemic effects. Muscle recovery, injury healing, and flexibility improvements at their peak.

Week 6+

Typically followed by a maintenance phase (once weekly) or a 2-4 week break.

Days 1-14

Loading phase. Most people don't feel dramatic changes yet, but tissue repair is happening beneath the surface.

Week 3-4

Improved range of motion and reduced stiffness commonly reported. Recovery between workouts feels faster.

Week 5-6

Full systemic effects. Muscle recovery, injury healing, and flexibility improvements at their peak.

Week 6+

Typically followed by a maintenance phase (once weekly) or a 2-4 week break.

Individual experiences vary. Results depend on your body, goals, and protocol adherence.

Can this be combined with other peptides?

BPC-157

Commonly paired

The "Wolverine Stack." BPC-157 heals locally, TB-500 heals systemically.

GHK-Cu

Works well together

Used for complex tissue damage and post-surgical healing.

CJC-1295 / Ipamorelin

Works well together

Adds growth hormone support to systemic tissue repair.

Thymosin Alpha-1

Sometimes combined

Both are thymosin-family peptides; combined for comprehensive immune and tissue support.

Explore the Wolverine Stack

How well researched is this?

Strong Animal & Lab Research

Extensive published studies on tissue repair and cell migration. Human clinical data is limited.

Want the full breakdown? Read our comprehensive analysis.

Read Evidence Review →

Legal status

Currently restricted by the FDA and cannot be legally compounded. This status may change — we'll update this page when it does.

2026 reclassification status updates coming soon.

Purity

Purity measures how clean and accurate the compound is. Higher purity means fewer contaminants and more reliable dosing.

>99.0%

HPLC Purity Tested

Always require a Certificate of Analysis (CoA) from a US-based compounding pharmacy.

Common questions

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