Also known as Bremelanotide (brand name Vyleesi). The only peptide specifically FDA-approved for treating low sexual desire in premenopausal women. Works through brain pathways, not blood flow like Viagra.
What is this used for?
What dose is typical for your goal?
- Typical dose
- 1–2 mg
- How it's taken
- Injection under the skin
- How often
- As needed, 1–2 hours before activity
- Most common starting point
- 1 mg to assess tolerance, then 1.5–2 mg. Do not use more than twice a week.
Based on published studies and what providers typically prescribe.
Important safety info
- FDA limit: max 8 doses per month, no more than 1 per 24 hours.
- Causes transient blood-pressure elevation (6–8 mmHg for 6–12 hours) — contraindicated in uncontrolled hypertension or known cardiovascular disease.
- FDA-approved only for premenopausal women with HSDD (Vyleesi). Other uses are off-label.
These are typical doses from research and real prescriptions — not a recommendation for you specifically. Your provider will adjust based on your body, your goals, and your health history.
Want your exact dose? A provider will personalize this for you.
Find a ProviderHow do you take it?
These are typical doses from research and real prescriptions — not a recommendation for you specifically. Your provider will adjust based on your body, your goals, and your health history.
What to expect
1 / 4Acute use
Effects typically begin 2-4 hours after injection, lasting 6-12 hours.
After 1-3 uses
Most people get a clear sense of whether this works for them.
Ongoing
PT-141 is typically used on-demand rather than daily. Not meant for continuous use.
Note
Unlike most peptides on this page, PT-141 is taken as-needed, not as a multi-week protocol.
Individual experiences vary. Results depend on your body, goals, and protocol adherence.
Can this be combined with other peptides?
How well researched is this?
Proven Human Clinical Research
FDA-approved as Vyleesi for premenopausal women. Extensive published studies for both men and women.
Legal status
This compound is an FDA-approved medication available by prescription.
Purity
Purity measures how clean and accurate the compound is. Higher purity means fewer contaminants and more reliable dosing.
HPLC Purity Tested
Always require a Certificate of Analysis (CoA) from a US-based compounding pharmacy.
Common questions
Ready to start?
Consult with a licensed provider to determine the right protocol for your goals.