INTRODUCTION

The most extensively studied cosmetic peptide in dermatology research. A collagen-stimulating peptide that tells your skin cells to produce more collagen and elastin from within — not just filling in wrinkles from the outside.

What is this used for?

Wrinkle Reduction

Wrinkle Reduction

Published clinical studies demonstrate up to 68% reduction in total wrinkle surface with consistent topical application. Works by mimicking a collagen breakdown signal to stimulate repair from within.

Collagen & Elastin Synthesis

Collagen & Elastin Synthesis

Studied for directly upregulating collagen I, III, and IV production in fibroblasts, as well as fibronectin and hyaluronic acid — building the structural scaffolding of youthful skin.

Skin Firmness & Texture

Skin Firmness & Texture

Clinical studies show significant improvements in skin elasticity, firmness, and surface texture with consistent use over 8–12 weeks, validated by skin measurement instruments rather than patient self-report alone.

How do you take it?

RouteTopical application
FrequencyTwice daily — morning and evening
Important Note

These are typical doses from research and real prescriptions — not a recommendation for you specifically. Your provider will adjust based on your body, your goals, and your health history.

How well researched is this?

Strong Animal & Lab Research

Multiple independent, controlled human clinical trials confirm efficacy on wrinkle depth, collagen synthesis, and skin firmness. One of very few cosmetic peptides with peer-reviewed clinical validation.

Want the full breakdown? Read our comprehensive analysis.
Read Evidence Review →

Purity

Purity measures how clean and accurate the compound is. Higher purity means fewer contaminants and more reliable dosing.

>98.0%

HPLC Purity Tested

Always require a Certificate of Analysis (CoA) from a US-based compounding pharmacy.

Common questions

Ready to start?

Consult with a licensed provider to determine the right protocol for your goals.